LAAC Clinical Application Seminar Tour- Zhejiang Stop

The LAAC Clinical Application Seminar Tour was initiated by China Atrial Fibrillation Center and organized by LifeTech Scientific. The seminar tour has received wide recognition since the first session was successfully held in Hubei province. Recently, LifeTech Scientific and the Zhejiang Province Atrial Fibrillation Alliance held the second session of the seminar tour to provide the guidance on the standardization of the LAAC procedure during the COVID-19 outbreak for cardiovascular doctors.


This seminar tour was hosted by well-known experts, including Professor Zheng Liangrong from the First Affiliated Hospital, College of Medicine, Zhejiang University, who is also the Chairman of the Zhejiang Province Atrial Fibrillation Alliance, Professor Huang He from Renmin Hospital of Wuhan University, Professor Wang Lihong from Zhejiang Provincial People’s Hospital, and Professor Jiang Chenyang from Sir Run Run Shaw Hospital, Zhejiang University School of Medicine. Moreover, many clinical experts from Zhejiang Province were also invited to share academic hotspots of Left Atrial Appendage Closure (LAAC) and procedures with the LAmbre™ Left Atrial Appendage Occluder (LAAO) system, to enhance doctors’ LAAC skills and to standardize the usage of anticoagulant.


Part of Online Attendees



Academic Exchanges

Professor Huang He from the Renmin Hospital of Wuhan University shared the latest academic progress of the LAAC. Professor Huang He concluded, recent studies such as ACC-NCDR (National Cardiovascular Data Registry), CAP / CAP2 (Five-year Follow-up Study) and PRAGUE (LAAC vs. NOAC) have further confirmed the safety and effectiveness of LAAC for the prevention of atrial fibrillation (AF) stroke. At the same time, the global LAAC guideline is being continuously refined based on the clinical data. In the future, LAAC will be heading to the personalized treatment under the guidance of 3D printing and other emerging technologies.  


The Latest Academic Progress and Clinical Research of LAAC - Professor Huang He


Professor Zheng Liangrong from the First Affiliated Hospital, College of Medicine, Zhejiang University, mainly shared the LAAC perioperative anticoagulation treatment strategy. Professor Zheng Liangrong emphasizeddue to the complex cause of thrombus formation, ACT (Activated Clotting Time) should be strictly monitored during the procedure to ensure the complete closure. It could greatly reduce the risk of device-related thrombus. At present, there is no guideline yet for the best anticoagulation treatment, so it is particularly important to follow-up the endothelialization and residual shunt through TEE. While the anticoagulation should be adjusted promptly based on the follow-up results.

LAAC Perioperative Anticoagulation Treatment Strategy-Professor Zheng Liangrong


The complication prevention of LAAC gains a great attention. Professor Jiang Chenyang of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, mainly discussed the prevention and management methods for three types of LAAC related complications (device-related embolization, pericardial effusion and device-related thrombus). It brought a warm discussion among the participants. 



Personalized Treatment and Post-procedure Complication Management of the LAAC - Professor Jiang Chenyang


LAmbre ™ Cases Sharing and Discussion

In the case discussion session, Professor Xiao Fangyi of the First Affiliated Hospital of Wenzhou Medical University, introduced the “partial distal deployment” technique through a double-lobed large LAA case. During the procedure, Professor Xiao Fangyi adopted the LT-LAA-2436 “small umbrella and big cover” specification of the LAmbre™ LAAO, achieving a satisfactory closure effect with the “partial distal deployment” technique. The technique ensures the 8 U-shaped hooks on the fixed disc being fully opened, makes the procedure could meet the high-quality COST criteria, reducing the risk of pericardial effusion.


Double-lobed Large LAA Case - Professor Xiao Fangyi


The unsatisfactory alignment usually brings difficulty in the LAAC. Professor Wang Yunfan from Zhejiang Provincial People’s Hospital shared an ultra-low-positioned LAAC case with the LAmbre™ device. The residual shunt risk of the procedure was minimized through the adjustment of the alignment, and it achieved a satisfactory closure effect.


An ultra-low-positioned LAA Case - Professor Wang Yunfan


Professor Du Xianfeng from the Ningbo First Hospital demonstrated an impressed double-lobed huge LAA case (ostial diameter is 40mm). The procedure adopted LAmbre™ LAAO with the specifications of LT-LAA-2228 and LT-LAA-2430 to close the LAA inferior edge and upper edge respectively. Two devices cling to each other, making a complete closure for the huge LAA. 

Challenge the Impossible, Dual Devices Close the Huge LAA - Professor Du Xianfeng


The LAAC Clinical Application Seminar Tour in Zhejiang Province closed successfully, and the next stop in Guangdong province will be coming soon!